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Adenosine Deaminase Severe Combined Immunodeficiency - Medical Condition Information

Adenosine Deaminase Severe Combined Immunodeficiency

ADA-SCID
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📋Overview

Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) is a rare genetic disorder characterized by a deficiency of the enzyme adenosine deaminase (ADA), leading to severe impairment of the immune system. ADA-SCID is a subtype of Severe Combined Immunodeficiency (SCID), a group of disorders causing profound defects in both T-cell and B-cell immunity. This condition results in extreme vulnerability to infections early in life. ADA deficiency leads to toxic metabolite accumulation that damages lymphocytes, causing immune failure.

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Medical codes (for reference)

UMLS CUI: C0392607
ICD-10-CM
D81.31
MeSH
C531816
SNOMED CT (US)
22406001

Codes are provided for reference and interoperability. They are not a diagnosis.

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