📋Overview
Adrenoleukodystrophy (ALD) is a genetic disorder characterized by the progressive degeneration of the nervous system and adrenal glands due to the accumulation of very long-chain fatty acids (VLCFAs). It is caused by mutations in the ABCD1 gene, leading to impaired peroxisomal metabolism. ALD primarily affects males and has several clinical variants, including childhood cerebral ALD, adrenomyeloneuropathy, and Addison-only disease.
Medical codes (for reference)
UMLS CUI: C0162309ICD-10-CM
E71.52E71.529
MeSH
D000326
SNOMED CT (US)
65389002
Codes are provided for reference and interoperability. They are not a diagnosis.
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