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Systemic Aleukemic Reticuloendotheliosis - Medical Condition Information

Systemic Aleukemic Reticuloendotheliosis

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📋Overview

Systemic Aleukemic Reticuloendotheliosis is a legacy term historically used to describe a rare, aggressive hematologic malignancy characterized by infiltration of malignant histiocytes (macrophage-like cells) in multiple organs without circulating malignant cells in the peripheral blood. It is now recognized as a form of histiocytic sarcoma or related histiocytic neoplasms under modern classification systems. The term 'aleukemic' refers to the absence of malignant cells in the blood despite systemic involvement.

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Medical codes (for reference)

UMLS CUI: C0019621
ICD-10-CM
C96.6
MeSH
D006646
SNOMED CT (US)
65399007110450007

Codes are provided for reference and interoperability. They are not a diagnosis.

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