Question 1

What is American Pawpaw (Asimina triloba)?

Accepted Answer

American pawpaw (Asimina triloba) is a North American fruit tree. While the ripe fruit is eaten as food, pawpaw contains acetogenins (including annonacin) that raise safety concerns about chronic or concentrated exposure (e.g., extracts).

Question 2

What are the common uses of American Pawpaw (Asimina triloba)?

Accepted Answer

American Pawpaw (Asimina triloba) is commonly used for Food use (ripe fruit), Marketed in some contexts as a source of ‘bioactive compounds’ (supplement/extract marketing; limited clinical evidence).

Question 3

How does American Pawpaw (Asimina triloba) work?

Accepted Answer

Pawpaw contains annonaceous acetogenins (including annonacin). Laboratory and clinical concern sources note annonacin can be neurotoxic in experimental settings, leading to caution against chronic use of concentrated pawpaw products/extracts.

Question 4

What are the side effects of American Pawpaw (Asimina triloba)?

Accepted Answer

Common side effects of American Pawpaw (Asimina triloba) may include Gastrointestinal upset (possible). Always consult with a healthcare professional before starting any supplement.

Question 5

Are there any warnings or precautions for American Pawpaw (Asimina triloba)?

Accepted Answer

Avoid chronic use of concentrated pawpaw extracts/products due to neurotoxicity concerns (annonacin) reported in scientific and clinical references. Avoid during pregnancy/breastfeeding. Additional precautions may apply.

Question 6

Does American Pawpaw (Asimina triloba) interact with medications or other supplements?

Accepted Answer

American Pawpaw (Asimina triloba) may interact with certain medical conditions. Always inform your healthcare provider about all medications and supplements you are taking.

Question 7

Is American Pawpaw (Asimina triloba) FDA approved?

Accepted Answer

In the U.S., products sold as dietary supplements are regulated under DSHEA; they are not FDA-approved for effectiveness before marketing, and quality/purity can vary by product.

Question 8

Where can I buy American Pawpaw (Asimina triloba)?

Accepted Answer

Ripe fruit is available seasonally/regionally as food in the U.S.; supplement/extract products exist but are less common and warrant caution.

American Pawpaw (Asimina triloba)

📋Overview

Common Uses

How It Works

Sources and Forms

Common Side Effects

Warnings and Precautions

Interactions

Regulatory Status

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