Question 1

What is Diiodothyronine?

Accepted Answer

Diiodothyronine in supplements typically refers to 3,5-diiodo-L-thyronine (T2), a thyroid-hormone–related compound marketed for fat loss or metabolism. It has thyroid-like (thyromimetic) activity in experimental research, and it raises significant safety and regulatory concerns as a supplement ingredient.

Question 2

What are the common uses of Diiodothyronine?

Accepted Answer

Diiodothyronine is commonly used for Marketed for weight loss/fat burning and ‘metabolism boosting’ (supplement marketing).

Question 3

How does Diiodothyronine work?

Accepted Answer

T2 is structurally related to thyroid hormones and can exert thyroid-like effects in experimental models, including effects on energy metabolism and the hypothalamus–pituitary–thyroid axis; this creates risk for thyroid disruption and cardiovascular side effects.

Question 4

What are the side effects of Diiodothyronine?

Accepted Answer

Common side effects of Diiodothyronine may include Potential for thyroid axis disruption (e.g., suppression/dysregulation), Potential cardiovascular stimulation (e.g., increased heart rate). Always consult with a healthcare professional before starting any supplement.

Question 5

Are there any warnings or precautions for Diiodothyronine?

Accepted Answer

Avoid use unless under medical supervision; thyroid-hormone–like compounds can cause serious harm. Do not use if you have thyroid disease, heart disease/arrhythmias, or are pregnant/breastfeeding. Additional precautions may apply.

Question 6

Does Diiodothyronine interact with medications or other supplements?

Accepted Answer

Diiodothyronine may interact with drugs such as Thyroid hormone medications (potential additive/unsafe thyroid effects), certain medical conditions. Always inform your healthcare provider about all medications and supplements you are taking.

Question 7

Is Diiodothyronine FDA approved?

Accepted Answer

FDA has objected to T2 being marketed as a dietary ingredient without appropriate safety demonstration/notification (NDI issues have been documented), and products may be considered adulterated depending on circumstances.

Question 8

Where can I buy Diiodothyronine?

Accepted Answer

Sold online in some weight-loss/sports supplement markets (despite safety/regulatory concerns).

Diiodothyronine

📋Overview

Common Uses

How It Works

Sources and Forms

Common Side Effects

Warnings and Precautions

Interactions

Regulatory Status

Availability

Frequently Asked Questions

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