Question 1

What is Sangre de Grado?

Accepted Answer

Sangre de grado (also called sangre de drago or “dragon’s blood”) commonly refers to the latex of Croton lechleri. A purified extract from this latex, crofelemer, has been developed and evaluated in clinical studies for secretory diarrhea and has an FDA drug application history as a botanical-derived active compound (distinct from raw latex supplements).

Question 2

What are the common uses of Sangre de Grado?

Accepted Answer

Sangre de Grado is commonly used for Traditional use in South America for diarrhea and wound healing (historical use), Studied as purified crofelemer for secretory diarrhea conditions (drug development context).

Question 3

How does Sangre de Grado work?

Accepted Answer

Crofelemer (purified proanthocyanidin oligomer from C. lechleri latex) has antisecretory effects in the intestine by modulating chloride channels involved in fluid secretion (mechanism described in research).

Question 4

Are there any warnings or precautions for Sangre de Grado?

Accepted Answer

Do not assume raw latex supplements match purified crofelemer studied/regulated in drug development; composition and dosing can differ substantially. For persistent or severe diarrhea, medical evaluation is important to rule out dehydration, infection, or other causes.

Question 5

Is Sangre de Grado FDA approved?

Accepted Answer

Raw “sangre de grado” is sold as a supplement in some markets and is not FDA-approved as a drug. Crofelemer is a purified drug substance derived from Croton lechleri latex with FDA review documentation in the Drugs@FDA context.

Question 6

Where can I buy Sangre de Grado?

Accepted Answer

OTC raw products online; crofelemer is available by prescription where approved/marketed.

Sangre de Grado

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